Cohesin mutations alter DNA damage repair and chromatin structure and create therapeutic vulnerabilities in MDS/AML

Edwin Chen; Z Tothova; AL Valton; RA Gorelov; M Vallurupalli; JM Krill-Burger; A Holmes; CC Landers; JE Haydu; E Malolepsza; C Hartigan; M Donahue; KD Popova; S Koochaki; SV Venev; J Rivera; K Lage; M Schenone; AD D'Andrea; SA Carr; EA Morgan; J Dekker; BL Ebert

Cohesin mutations alter DNA damage repair and chromatin structure and create therapeutic vulnerabilities in MDS/AML

Edwin Chen
, Z Tothova
, AL Valton
, RA Gorelov
, M Vallurupalli
, JM Krill-Burger
, A Holmes
, CC Landers
, JE Haydu
, E Malolepsza
, C Hartigan
, M Donahue
, KD Popova
, S Koochaki
, SV Venev
, J Rivera
, K Lage
, M Schenone
, AD D'Andrea
, SA Carr

EA Morgan, J Dekker, BL Ebert

Research output: Contribution to journal › Article › peer-review

75 Citations (Scopus)

Original language	English
Pages (from-to)	e142149
Journal	JCI Insight
Volume	6
Publication status	Published - 2021

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Cite this

Chen, E., Tothova, Z., Valton, AL., Gorelov, RA., Vallurupalli, M., Krill-Burger, JM., Holmes, A., Landers, CC., Haydu, JE., Malolepsza, E., Hartigan, C., Donahue, M., Popova, KD., Koochaki, S., Venev, SV., Rivera, J., Lage, K., Schenone, M., D'Andrea, AD., ... Ebert, BL. (2021). Cohesin mutations alter DNA damage repair and chromatin structure and create therapeutic vulnerabilities in MDS/AML. JCI Insight, 6, e142149.

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title = "Cohesin mutations alter DNA damage repair and chromatin structure and create therapeutic vulnerabilities in MDS/AML",

author = "Edwin Chen and Z Tothova and AL Valton and RA Gorelov and M Vallurupalli and JM Krill-Burger and A Holmes and CC Landers and JE Haydu and E Malolepsza and C Hartigan and M Donahue and KD Popova and S Koochaki and SV Venev and J Rivera and K Lage and M Schenone and AD D'Andrea and SA Carr and EA Morgan and J Dekker and BL Ebert",

year = "2021",

language = "English",

volume = "6",

pages = "e142149",

journal = "JCI Insight",

issn = "2379-3708",

publisher = "American Society for Clinical Investigation",

}

Chen, E, Tothova, Z, Valton, AL, Gorelov, RA, Vallurupalli, M, Krill-Burger, JM, Holmes, A, Landers, CC, Haydu, JE, Malolepsza, E, Hartigan, C, Donahue, M, Popova, KD, Koochaki, S, Venev, SV, Rivera, J, Lage, K, Schenone, M, D'Andrea, AD, Carr, SA, Morgan, EA, Dekker, J & Ebert, BL 2021, 'Cohesin mutations alter DNA damage repair and chromatin structure and create therapeutic vulnerabilities in MDS/AML', JCI Insight, vol. 6, pp. e142149.

TY - JOUR

T1 - Cohesin mutations alter DNA damage repair and chromatin structure and create therapeutic vulnerabilities in MDS/AML

AU - Chen, Edwin

AU - Tothova, Z

AU - Valton, AL

AU - Gorelov, RA

AU - Vallurupalli, M

AU - Krill-Burger, JM

AU - Holmes, A

AU - Landers, CC

AU - Haydu, JE

AU - Malolepsza, E

AU - Hartigan, C

AU - Donahue, M

AU - Popova, KD

AU - Koochaki, S

AU - Venev, SV

AU - Rivera, J

AU - Lage, K

AU - Schenone, M

AU - D'Andrea, AD

AU - Carr, SA

AU - Morgan, EA

AU - Dekker, J

AU - Ebert, BL

PY - 2021

Y1 - 2021

M3 - Article

SN - 2379-3708

VL - 6

SP - e142149

JO - JCI Insight

JF - JCI Insight

ER -