Recent Advances in the Oncology of Invertebrate Species

Sarah Pellett; Michelle F. O’Brien; Andrew F. Rich; Carol M. Trim

doi:10.1016/j.cvex.2025.12.003

Recent Advances in the Oncology of Invertebrate Species

Sarah Pellett
, Michelle F. O’Brien
, Andrew F. Rich
, Carol M. Trim

Natural Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

This review explores the emerging field of invertebrate oncology, highlighting the challenges in diagnosis and treatment across diverse taxa. It discusses tumor development mechanisms, age-related changes, and the rarity of confirmed neoplasms in terrestrial invertebrates, contrasted with more extensive research in aquatic species. Diagnostic methods such as imaging, cytology, and histopathology are outlined, alongside limited treatment options including experimental chemotherapies and surgical removal. The article emphasizes the importance of reporting and studying invertebrate neoplasia to enhance understanding, improve diagnostics, and develop effective treatments, supporting the growing role of invertebrates in zoos, research, and pet industries. [Abstract copyright: Copyright © 2025 Elsevier Inc. All rights reserved.]

Original language	English
Journal	Veterinary Clinics of North America - Exotic Animal Practice
Early online date	17 Feb 2026
DOIs	https://doi.org/10.1016/j.cvex.2025.12.003
Publication status	E-pub ahead of print - 17 Feb 2026

Keywords

Diagnosis
Histology
Invertebrate
Neoplasia
Oncology
Transmissible cancer
Treatment

Access to Document

10.1016/j.cvex.2025.12.003Licence: All rights reserved

Cite this

@article{e249268479584c1085c3dfdbc9b3d53d,

title = "Recent Advances in the Oncology of Invertebrate Species",

abstract = "This review explores the emerging field of invertebrate oncology, highlighting the challenges in diagnosis and treatment across diverse taxa. It discusses tumor development mechanisms, age-related changes, and the rarity of confirmed neoplasms in terrestrial invertebrates, contrasted with more extensive research in aquatic species. Diagnostic methods such as imaging, cytology, and histopathology are outlined, alongside limited treatment options including experimental chemotherapies and surgical removal. The article emphasizes the importance of reporting and studying invertebrate neoplasia to enhance understanding, improve diagnostics, and develop effective treatments, supporting the growing role of invertebrates in zoos, research, and pet industries. [Abstract copyright: Copyright {\textcopyright} 2025 Elsevier Inc. All rights reserved.]",

keywords = "Diagnosis, Histology, Invertebrate, Neoplasia, Oncology, Transmissible cancer, Treatment",

author = "Sarah Pellett and O{\textquoteright}Brien, \{Michelle F.\} and Rich, \{Andrew F.\} and Trim, \{Carol M.\}",

year = "2026",

month = feb,

day = "17",

doi = "10.1016/j.cvex.2025.12.003",

language = "English",

journal = "Veterinary Clinics of North America - Exotic Animal Practice",

issn = "1094-9194",

publisher = "W.B. Saunders",

}

TY - JOUR

T1 - Recent Advances in the Oncology of Invertebrate Species

AU - Pellett, Sarah

AU - O’Brien, Michelle F.

AU - Rich, Andrew F.

AU - Trim, Carol M.

PY - 2026/2/17

Y1 - 2026/2/17

N2 - This review explores the emerging field of invertebrate oncology, highlighting the challenges in diagnosis and treatment across diverse taxa. It discusses tumor development mechanisms, age-related changes, and the rarity of confirmed neoplasms in terrestrial invertebrates, contrasted with more extensive research in aquatic species. Diagnostic methods such as imaging, cytology, and histopathology are outlined, alongside limited treatment options including experimental chemotherapies and surgical removal. The article emphasizes the importance of reporting and studying invertebrate neoplasia to enhance understanding, improve diagnostics, and develop effective treatments, supporting the growing role of invertebrates in zoos, research, and pet industries. [Abstract copyright: Copyright © 2025 Elsevier Inc. All rights reserved.]

AB - This review explores the emerging field of invertebrate oncology, highlighting the challenges in diagnosis and treatment across diverse taxa. It discusses tumor development mechanisms, age-related changes, and the rarity of confirmed neoplasms in terrestrial invertebrates, contrasted with more extensive research in aquatic species. Diagnostic methods such as imaging, cytology, and histopathology are outlined, alongside limited treatment options including experimental chemotherapies and surgical removal. The article emphasizes the importance of reporting and studying invertebrate neoplasia to enhance understanding, improve diagnostics, and develop effective treatments, supporting the growing role of invertebrates in zoos, research, and pet industries. [Abstract copyright: Copyright © 2025 Elsevier Inc. All rights reserved.]

KW - Diagnosis

KW - Histology

KW - Invertebrate

KW - Neoplasia

KW - Oncology

KW - Transmissible cancer

KW - Treatment

UR - https://www.scopus.com/pages/publications/105035168890

U2 - 10.1016/j.cvex.2025.12.003

DO - 10.1016/j.cvex.2025.12.003

M3 - Article

SN - 1094-9194

JO - Veterinary Clinics of North America - Exotic Animal Practice

JF - Veterinary Clinics of North America - Exotic Animal Practice

ER -

Recent Advances in the Oncology of Invertebrate Species

Abstract

Keywords

Access to Document

Other files and links

Embargoed Document

Fingerprint

Cite this