Role of Plasma Inflammatory and Blood Biomarkers in Cerebral Small Vessel Disease

Adan Khan; Leezza Faboro Davidson; Benjamin Yip; Lisa Chelikani; Lewis Courtnage; Soban Sadiq; Momina Riaz Siddiqui; Fatima Faraz

doi:10.1201/9781003481621-6

Role of Plasma Inflammatory and Blood Biomarkers in Cerebral Small Vessel Disease

Adan Khan
, Leezza Faboro Davidson
, Benjamin Yip
, Lisa Chelikani
, Lewis Courtnage
, Soban Sadiq
, Momina Riaz Siddiqui
, Fatima Faraz

Kent and Medway Medical School (KMMS)

Kent Medway Medical School
Rawalpindi Medical College

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Cerebral small vessel disease (CSVD) is a significant contributor to cognitive decline, stroke, and dementia. This chapter explores the role of biomarkers in CSVD, examining their potential in diagnosis, prognosis, and disease monitoring. We discuss various biomarkers related to endothelial dysfunction, inflammation, and neuroimaging features. The chapter highlights the clinical implications of these biomarkers, current challenges in their application, and future directions in CSVD biomarker research. Emerging technologies, multi-marker approaches, and the potential for personalized medicine are considered. While significant progress has been made, further research is needed to fully realize the potential of biomarkers in improving CSVD management and patient outcomes.

Original language	English
Title of host publication	Cutting-Edge Diagnostic Technologies in Cardiovascular Diseases
Subtitle of host publication	Towards Data-Driven Smart Healthcare
Editors	Haipeng Liu, Gary Tse
Publisher	CRC Press
Pages	92-111
Number of pages	20
ISBN (Electronic)	9781040357248
ISBN (Print)	9781032771694
DOIs	https://doi.org/10.1201/9781003481621-6
Publication status	Published - 1 Jan 2025

Keywords

Cerebral small vessel disease
Plasma
Blood
Biomarkers

Access to Document

10.1201/9781003481621-6

Cite this

Khan, A., Davidson, L. F., Yip, B., Chelikani, L., Courtnage, L., Sadiq, S., Siddiqui, M. R., & Faraz, F. (2025). Role of Plasma Inflammatory and Blood Biomarkers in Cerebral Small Vessel Disease. In H. Liu, & G. Tse (Eds.), Cutting-Edge Diagnostic Technologies in Cardiovascular Diseases: Towards Data-Driven Smart Healthcare (pp. 92-111). CRC Press. https://doi.org/10.1201/9781003481621-6

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abstract = "Cerebral small vessel disease (CSVD) is a significant contributor to cognitive decline, stroke, and dementia. This chapter explores the role of biomarkers in CSVD, examining their potential in diagnosis, prognosis, and disease monitoring. We discuss various biomarkers related to endothelial dysfunction, inflammation, and neuroimaging features. The chapter highlights the clinical implications of these biomarkers, current challenges in their application, and future directions in CSVD biomarker research. Emerging technologies, multi-marker approaches, and the potential for personalized medicine are considered. While significant progress has been made, further research is needed to fully realize the potential of biomarkers in improving CSVD management and patient outcomes.",

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doi = "10.1201/9781003481621-6",

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Khan, A, Davidson, LF, Yip, B, Chelikani, L, Courtnage, L, Sadiq, S, Siddiqui, MR & Faraz, F 2025, Role of Plasma Inflammatory and Blood Biomarkers in Cerebral Small Vessel Disease. in H Liu & G Tse (eds), Cutting-Edge Diagnostic Technologies in Cardiovascular Diseases: Towards Data-Driven Smart Healthcare. CRC Press, pp. 92-111. https://doi.org/10.1201/9781003481621-6

Role of Plasma Inflammatory and Blood Biomarkers in Cerebral Small Vessel Disease. / Khan, Adan; Davidson, Leezza Faboro; Yip, Benjamin et al.
Cutting-Edge Diagnostic Technologies in Cardiovascular Diseases: Towards Data-Driven Smart Healthcare. ed. / Haipeng Liu; Gary Tse. CRC Press, 2025. p. 92-111.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

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AU - Khan, Adan

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AU - Courtnage, Lewis

AU - Sadiq, Soban

AU - Siddiqui, Momina Riaz

AU - Faraz, Fatima

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AB - Cerebral small vessel disease (CSVD) is a significant contributor to cognitive decline, stroke, and dementia. This chapter explores the role of biomarkers in CSVD, examining their potential in diagnosis, prognosis, and disease monitoring. We discuss various biomarkers related to endothelial dysfunction, inflammation, and neuroimaging features. The chapter highlights the clinical implications of these biomarkers, current challenges in their application, and future directions in CSVD biomarker research. Emerging technologies, multi-marker approaches, and the potential for personalized medicine are considered. While significant progress has been made, further research is needed to fully realize the potential of biomarkers in improving CSVD management and patient outcomes.

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KW - Blood

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A2 - Liu, Haipeng

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PB - CRC Press

ER -

Role of Plasma Inflammatory and Blood Biomarkers in Cerebral Small Vessel Disease

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Keywords

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